Antonis Antoniou

Professor of Cancer Risk Prediction, Department of Public Health and Primary Care, University of Cambridge

Professor Antoniou, a genetic epidemiologist, has made major contributions to the
understanding of the genetic basis of common cancers and the development of multifactorial cancer risk prediction models. Using innovative approaches to analyse data from large-scale studies, he has provided reliable estimates of cancer risks for high- and moderate-risk cancer susceptibility genes.

He leads the coordinating centre of the Consortium of Modifiers of BRCA1/2 and has demonstrated the clinical importance of genetic modifiers of cancer risk for BRCA1/2 carriers. He led the development of the multifactorial BOADICEA breast and ovarian cancer risk model. Endorsed by clinical guidelines in several countries and implemented into the CanRisk tool, it is used globally to counsel thousands of patients daily, to guide decisions on cancer screening and prevention.

In 2023, he was appointed director of the CRUK, Cancer Data Driven Detection (CD3) initiative.

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